The twisted ion-permeation pathway of a resting voltage-sensing domain
Article Abstract:
A structure-guided perturbation analysis of the omega conductance is performed to map its voltage-sensing domain (VSD) permeation pathway. The results have provided a model of the resting conformation of the VSD and have suggested that the key to conformational change in a VSD is a screw motion and a change in tilt of S4 helix, which either control the gate of a separate pore domain or remove a blocking arginine residue from a twisted VSD conduction pathway.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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A proteoglycan mediates inductive interaction during plant vascular development
Article Abstract:
Inductive cell-cell interactions are essential for controlling cell fate determination in both plants and animals. A molecule named xylogen mediates an inductive cell-cell interaction involved in plant tissue differentiation.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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