Two chemosensory receptors together mediate carbon dioxide detection in Drosophila

Article Abstract:

The C[O.sub.2]-responsive neurons in Drosophila have co-expressed a pair of chemosensory receptors, Gr21a and Gr63a, at both larval and adult life stages, which are enough for olfactory C[O.sub.2]-chemosensation in Drosophila. The molecular identity of the insect olfactory C[O.sub.2] receptors might develop a novel mosquito control strategies designed to take advantage of this unique and critical olfactory pathway.

Germany, Analysis, In situ hybridization, Immunofluorescence, Fluorescent antibody technique, Olfactory receptors

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Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase

Article Abstract:

Drosophila translationally controlled tumour protein (dTCTP) is shown to be an essential new component of the tuberous sclerosis (TSC)-Rheb (Ras homologue enriched in brain) pathway. The results have shown that the function of TCTP in the TSC pathway is evolutionarily conserved and it has also identified TCTP as a direct regulator of Rheb and a potential therapeutic target for TSC disease.

Texas, Causes of, Risk factors, Tumor proteins, Tuberous sclerosis, T cell proliferation, Tumour proteins

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