2,3,7,8-Tetrachlorodibenzo-p-dioxin affects fluctuating asymmetry of molar shape in mice, and an epistatic interaction of two genes for molar size

Article Abstract:

The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the fluctuatin asymmetry (FA) of molar shape in mice, which is produced from an intercross between two inbred strains, is examined. The results have shown that although TCDD might affect the expression of some genes governing the development of molars in mice, the FA of molar size and shape is not particularly sensitive indicator of this effect.

Pesticide and Other Agricultural Chemical Manufacturing, Agricultural chemicals, not elsewhere classified, Dioxin, Gene expression, Dioxins

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Genome-wide characterisation of Hepatitis B mutations involved in clinical outcome

Article Abstract:

HBV genomes of Hepatitis B were investigated to study the different states of the disease such as acute, chronic and fulminant infection and the outcome of such infection. Results suggest that the genetic composition of the infective HBV strains is a major determinant of clinical outcome and disease outcome can be predicted to a large extent with a limited number of host and viral factors.

United Kingdom, Science & research, Research, Gene mutations, Gene mutation, Genetic aspects, Phylogeny, Hepatitis B virus

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