Axon guidance molecules
Article Abstract:
A multifactorial approach is used to explain the nature and mechanism of axon guidance molecules in target recognition. One model explains the role of chemoattractants such as netrins as an important guidance mechanism. Another model proposes that netrins also influence the selection of the direction of growth cone development by a chemorepulsive mechanism.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
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Pars, PI 3-kinase and the establishment of neuronal polarity
Article Abstract:
The author comments on the studies of the protein complex which consists of mPar3, mPar6 and atypical proteins kinase C. The topics of interest include selective localization of the complex to the cultured hippocampal neurons' anoxal growth cone.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
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Regulating axon branch stability; the role of p190 RhoGAP in repressing a retraction signaling pathway
Article Abstract:
The axon stability is mediated by p190 Rho GTpase activating protein as indicated by axon branch retraction following p190 inactivation. Data suggest that a retraction pathway from RhoA to myosin in maturing neurons is repressed by p190.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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