Probing bacterial nucleoid structure with optical tweezers

Article Abstract:

The H-NS protein, a major component of the nucleoid in Gram-negative bacterial cells, forms bridges between different DNA molecules or between different sections of the same molecule, facilitating it to compact and impose structure on nucleoid. New insights into H-NS mediated DNA bridging that were obtained using tweezers device are described.

Analysis, Gram-negative bacteria, Nuclear magnetic resonance spectroscopy, Heat shock proteins, DNA-ligand interactions, DNA binding

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Size assessment and growth control: How adult size is determined in insects

Article Abstract:

The mechanisms responsible for controlling growth rates and size assessment in insects are discussed. Researchers have found that the insulin-dependent growth of the prothoracic gland is involved in assessing when critical weight is reached and mutations in DHR4, a repressor of ecdysone signaling, reduce critical weight and adult size.

Growth, Drosophila, Insulin, Endocrine glands, Insulin structure-activity relationships, Company growth, Larval development

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