The relationship between synapsis and recombination: two different views
Article Abstract:
The relationship between recombination and synapsis has been studied from two points of view. The traditional view is that synaptonemal complex (SC) formation gives a framework for initiation of crossing over, mainly based on observations of chiasmata occurring only in yeast chromosomal regions where there is an SC. Crossovers are assumed not to start until synapsis ends. Recombination is necessary for synapsis. There is however, experimental support for the view that there is another view of the relationship of synapsis to recombination. Some question whether recombination is required for synapsis in higher eukaryotes. Detailed study of zygotene complements have been carried out mostly in plant chromosomes. That may be because their axial elements are easier to stain than those of animals. Data on gene conversion events on higher eukaryotes are very few because of technical difficulties.
Publication Name: Heredity
Subject: Biological sciences
ISSN: 0018-067X
Year: 1999
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Ethics of reconstructing a Spanish Flu: It is wise to resurrect a deadly virus?
Article Abstract:
The full sequence of a highly virulent strain of influenza, called the Spanish Flu that was extinct till 2006 is published and reconstructed in 2007. The virus, which killed up to 50 million people worldwide, proved to be as fatal as the original when tested on mice, killing them more quickly than any other flu. Hence, with the resurrection of this Spanish Flu, it is advised that there is a need for biosecurity regulations to prevent the proliferation of particularly dangerous knowledge.
Publication Name: Heredity
Subject: Biological sciences
ISSN: 0018-067X
Year: 2007
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Merging protein, gene and genomic data: The evolution of the MDR-ADH family
Article Abstract:
Multiple members of the MDR-ADH (MDR: Medium-chain dehydrogenases/reductases; ADH: alcohol dehydrogenase) family are found in vertebrates, although the enzymes that belong to this family is isolated from bacteria, yeast, plant and animal sources. The data available provides a comprehensive scenario, from which a reliable picture of the evolutionary history of this family can be made.
Publication Name: Heredity
Subject: Biological sciences
ISSN: 0018-067X
Year: 2005
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