Estimates of gene flow in Drosophila pseudoobscura determined from nucleotide sequence analysis of the alcohol dehydrogenase region
Article Abstract:
Nucleotide sequence analysis was performed on a 3.4 kilobase region of the alcohol dehydrogenase gene from 99 isochromosomal strains from 13 Drosophila pseudoobscura populations and from two sibling species to characterize the genetic structure of fruit fly populations. No substructure was identified among North American D. pseudoobscura populations. The diversity in nucleotide sequences agrees well with measures of gene flow and indicates extensive exchange between different D. pseudoobscura populations.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
Rates of synonymous substitution and base composition of nuclear genes in Drosophila
Article Abstract:
Comparison of the rates of synonymous substitution within various genes in a number of Drosophila species revealed significant variation in these rates among evolutionary lines. Large variations among nuclear genes were also discovered. The rates of synonymous substitution correlated with gene nucleotide composition. In addition, analysis of pseudogenes and their functional homologs showed that the substitutions were affected by the organism's biased mutation pattern.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
Molecular population genetics of an electrophoretically monomorphic protein in the alcohol dehydrogenase region of Drosophila pseudoobscura
Article Abstract:
A low rate of neutral mutation causes amino acid polymorphism deficiency in the alcohol dehydrogenase (Adh) region of Drosophila pseudoobscura. The nucleotide sequence data of 18 alleles of the (Adh) region were analyzed for deviations from an equilibrium neutral model. The Tajima test and the Hudson, Kreitman and Aguade test were used to test the nucleotide sequence data.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Estimation of levels of gene flow from DNA sequence data. Deleterious background selection with recombination
- Abstracts: Promoter elements in Drosophila melanogaster revealed by sequence analysis. Genetic analysis of the Additional sex combs locus of Drosophila melanogaster
- Abstracts: Genetic studies of mei-1 gene activity during the transition from meiosis to mitosis in Caenorhabditis elegans