Expression studies on four members of the pMGA multigene family in Mycoplasma gallisepticum S6
Article Abstract:
The S6 strain of the bacterial pathogen Mycoplasma gallisepticum expresses the pMGA1.1 gene only and contains transcripts of three other pMGA genes. The concentration of the pMGA1.1 transcript is more than other pMGA genes and the widely expressed tuf gene. The restriction of gene expression to a pMGA gene occurs mainly via a transcriptional method but probably involves other methods also. The pMGA genes have a single transcription initiation site and the mRNA is monocistronic. The R and F strains also express only one pMGA gene.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1995
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A gene family in Mycoplasma imitans closely related to the pMGA family of Mycoplasma gallisepticum
Article Abstract:
Research was conducted to examine several members of the pneumoniae group, which includes Mycoplasma imitans, M. iowae, M. genitalium, M. penetrans, M. pirum and M. pneumoniae, for proteins homologous to pMGA and for gene families which may encode them. The identification of three gene families that are recognized as homologous in three phylogenetically distinct avian mycoplasma species, but not in human mycoplasmas, indicates a horizontal transfer between species infecting the same host.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
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Size and genomic location of the pMGA multigene family of Mycoplasma gallisepticum
Article Abstract:
The size of the surface antigen and hemagglutinin (pMGA) gene family varies significantly among strains of Mycoplasma gallisepticum. The size and location of the genomic family were determined using Southern blotting and gel electrophoresis. The number of copies in the genome ranges from 32 in strain F to 70 in strain R. The hybridizing regions are located at four separate places on the chromosome. The pMGA genes appear to be arranged in the regions as tandem repeats.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1996
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