HTP1 dependent constraints coordinate homolog pairing and synapsis and promote chiasma formation during C. elegans meiosis
Article Abstract:
Synaptonemal complex (SC) assembly must occur between correctly paired homologous chromosomes to promote formation of chiasmata and Caenorhabditis elegans HORMA-domain protein HTP1 for coordinating establishment of homolog pairing and synapsis in C. elegans. It is suggested that HTP1 mutants are defective in preventing the use of sister chromatids as recombination partners and model is proposed in which HTP1 functions to establish multiple constraints that lead to chiasmata formation.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans
Article Abstract:
Evidence that efficient export of a fibrolast growth factor (FGF), EGL-17 from the caenorhabditis elegans developing vulva involves the lipoprotein receptor-related proteins Ce-LRP-1 and Ce-LRP-2 and a cytoplasmic adaptor proteinCe-DAB-1 (Disabled) is reported. A model is suggested in which Ce-DAb-1 coordinates selection of receptor and cargo for transport through the secretory pathway.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
Reelin-induced tryosine phosphorylation of Disabled 1 during neuronal positioning
Article Abstract:
The brain's developmental reelin function regulates neuronal positioning. The intracellular disabled 1 gene gets a tryosine phosphorylation signal from reelin protein outside cells. The reelin and disabled 1 functions are interdependent, with disabled 1 phosphorylation stimulated by exogenous reelin.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Relationship of the cAMP-dependent protein kinase pathway to the SNF1 protein kinase and invertase expression in Saccharomyces cerevisiae
- Abstracts: Conjugational recombination in Escherichia coli: genetic analysis of recombinant formation in Hfr X F- crosses
- Abstracts: Utilization of carbon substrates, electrophoretic enzyme patterns, and symbiotic performance of plasmid-cured clover rhizobia
- Abstracts: AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif
- Abstracts: CcpA-dependent carbon catabolite repression in bacteria. The selective value of bacterial shape. Listeria monocytogenes surface proteins: from genome predictions to function