Inbreeding reduces power-law scaling in the distribution of fluctuating asymmetry: An explanation of the basis of developmental instability

Article Abstract:

A new model is presented for the phenomenological basis of fluctuating asymmetry, namely, that variation in fluctuating asymmetry is in large part due to the random exponential growth of cell populationsm, geometric Brownian motion that are terminated randomly around a genetically programmed development time. The results suggest that the kurtosis parameter of the fluctuating asymmetry distribution might provide more information about fluctuating asymmetry response than does a populations' average or mean fluctuating asymmetry.

United States, Analysis, Brownian motion, Gaussian distribution, Normal distribution, Cell populations

---

Calculating risk changes after negative mutation test outcomes for autosomal dominant hereditary late-onset disorders

Article Abstract:

A hypothetical pedigree of a family at risk of Huntington's disease was used to demonstrate the consequences for the risk status of various family members in the case where relatives were tested and found to be mutation negative. It was argued that accurate assessment of conditional probabilities in clinical genetics is important for individuals at risk for hereditary disorders with Mendelian transmission patterns.

Risk factors, Bayesian statistical decision theory, Bayesian analysis, Mendel's law, Mendel's laws, Huntington's chorea, Huntington's disease, Pedigree analysis

---

Seeing the light: The role of inherited developmental cascades in the origins of vertebrate lenses and their crystallins

Article Abstract:

The origins of lenses that allow animals to focus an image are a significant aspect of vision research. Investigations showed that all vertebrates and invertebrates used a similar cascade of proteins regulating gene expression in eye development.

Eye, Vision research, Lenses, Lenses (Optics)

Similar abstracts:

• Abstracts: Origin and evolution of gnathostome dentitions: A question of teeth and pharyngeal denticles in placoderms. The fundamental processes in ecology: a thought experiment in extraterrestrial biospheres
• Abstracts: 2,3,7,8-Tetrachlorodibenzo-p-dioxin affects fluctuating asymmetry of molar shape in mice, and an epistatic interaction of two genes for molar size
• Abstracts: Genetic correlates of phenotypic variation in the pocket gopher (Thomomys bottae) in California. Inherited Occipital Hypoplasia/Syringomyelia in the Cavalier King Charles Spaniel: Experiences in Setting Up a Worldwide DNA Collection
• Abstracts: What have tissue culture studies told us about the development of oligodendrocytes?

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.