Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis
Article Abstract:
A functional fusion of flagellin receptor FLS2 (in Arabidopsis) to the green fluorescent protein (GFP) resides in cell membranes of most tissues. Stimulation with the flagellin epitope flg22 induces its transfer into intracellular mobile vesicles, followed by degradation, and therefore it confirms that plant cells regulate pathogen-associated molecular pattern (PAMP)-mediated pattern recognition activities by subcellular compartmentalization.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2006
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Identification and characterization of two novel classes of small RNAs in the mouse germline: Retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
Article Abstract:
Two novel classes of small RNAs in the mouse germline are identified and addition of retrotransposon-derived sequences to the 3' untranslated region (UTR) of a reporter mRNA destabilizes the mRNA significantly when injected into full-grown oocytes. These results suggest that retroransposons are suppressed through the RNAi pathway in mouse oocytes.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2006
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