Lysine acetylation and the bremodomain: A new partnership for signaling
Article Abstract:
The modification in lysine acetylation is reversible in vivo, with its specialty and level being largely controlled by signal-dependent association of substracts with acetyltransferases and deacetylases. The recognition of acetyllysine by bromodomains reiterates the signaling principle that a modified residue serves as a ligand or generates a binding site for protein modules to be able to recognize the modification.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
Forces maintaining organellar genomes: Is any as strong as genetic code disparity or hydrophobicity
Article Abstract:
All genes that might be thought to imply the existence of a barrier to organellar gene transfer comparable in severity to code disparity and hydrophobicity are identified. It is shown that none of them actually implies this possibility and in particular, no functional property of organellar proteins such as involvement in redox processes, appears to be invoked as a more serious barrier.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Genetic variation in the free-living amoeba Naegleria fowleri. Assessing the risk of primary amoebic meningoencephalitis from swimming in the presence of environmental Naegleria fowleri
- Abstracts: Physical interaction of the retinoblastoma protein with human D cyclin. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
- Abstracts: Proliferation of mouse primordial germ cells in vitro: a key role for cAMP. Zebrafish Staufen1 and Staufen2 are required for the survival and migration of primordial germ cells
- Abstracts: Evaluation of the DNA fingerprinting method AFLP as a new tool in bacterial taxonomy. Biphasic kinetics of growth and bacteriocin production with Lactobacillus amylovorus DCE 471 occur under stress conditions
- Abstracts: Pathways of intracellular communication: tetrapyrroles and plastid-to-nucleus signaling. Checkpoint signaling: epigenetic events sound the DNA strand-breaks alarm to the ATM proein kinase