Meiotic proteins Bqt1 and Bqt2 tether telomeres to form the bouquet arrangement of chromosomes
Article Abstract:
Schizosaccharomyces pombe Sad 1 with two proteins, Bqt1 and Bqt2 act as a connector mediates movements of telomeres insides the nucleus. It is demonstrated that Sad1 and possibly SUN domain proteins in general are capable of moving specific chromosomal loci along nuclear membranes by linking the cytoskeletal network to chromsomes via developmentally expressed connector proteins such as Bqt1 and Bqt2.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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The meiotic chromosomal bouquet: SUN collects flowers
Article Abstract:
All telomeres in the cell attach to nuclear envelope in the early stages of meiosis and gather near centrosome, this polarized chromosomal array is known as bouquet as clustered telomeres resemble gathered stems of a floral arrangement. Intriguing clues about the molecular details underlying this conserved meiotic event is provided.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
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