Move it on over: getting proteins across biological membranes
Article Abstract:
This article discusses the translocation of macromolecules such as proteins across biological membranes. Research shows that the translocation system varies in composition depending upon whether it is signal-gated or signal-assembled. The system deploys components that are unique to the system such as translocons and translocon helpers.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2003
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Investigating protein-protein interfaces in bacterial transcription complexes: a fragmentation approach
Article Abstract:
Research examines a novel sequence within sigma(sup)54-dependent transcriptional activators making up a sigma(sup)54-binding interface. Data indicate that this binding interface is dynamic and exhibits nucleotide-dependent movement that controls output of ATPases associated with various cellular activities (AAA+) proteins.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2003
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The spliceosome: the most complex macromolecular machine in the cell?
Article Abstract:
The ribonucleoprotein complex spliceosome, involved in the splicing of introns, is composed of 300 proteins and five RNAs. It is the most complex macromolecular machine and the complexity is due to its criticl role in catalysis, quality control role(s) in mRNA synthesis, and its links to other nuclear machines.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2003
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