Planar cell polarity signaling in vertebrates
Article Abstract:
The morphological development of the mammalian organ of Corti is described for the interpretation of the emerging data and the molecular mechanisms are proposed for the underlying planar cell polarity (PCP) signaling in vertebrates. The analysis has shown that the organ of Corti has emerged as an excellent model system to illustrate the multiple cellular processes controlled by vertebrate PCP signaling.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
The molecular basis of neurosensory cell formation in ear development: A blueprint for hair cell and sensory neuron regeneration?
Article Abstract:
The molecular basis of neurosensory development in the mouse ear is explored to provide a blueprint for possible enhancement of therapeutically useful transformation of stem cells into lost neurosensory cells. The use of stem cells combined with molecular insights into neurosensory cell specification and proliferation regulation of the ear might help in the neurosensory regeneration of mammalian ears.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Development and maintenance of ear innervation and function: lessons from mutations in mouse and man
Article Abstract:
Mouse mutations that bring developmental ear defects and those that affect the formation or maintenance of sensory neurons in the hearing or vestibular systems are discussed as are several human genes from which molecular analysis of hearing disorders can proceed. It is argued that the ear is a system with unique advantages for study of developing sensory systems.
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Inheritance, allelism, and morphological characterization of unifoliate mutations in common bean. Identification of RFLP markers linked to the unifoliate leaf, cauliflower head mutation of alfalfa
- Abstracts: Astrovirus survival in drinking water. Isolation and identification of Helicobacter spp. from canine and feline gastric mucosa
- Abstracts: Microbial diversity associated with odor modification for production of fertilizers from chicken litter. Use of pulsed-field gel electrophoresis to link sporadic cases of invasive listeriosis with recalled chocolate milk
- Abstracts: X-linked dyskeratosis congenita is predominantly caused by missense mutations in the DKC1 gene. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
- Abstracts: Ectoderm-mesenchyme and mesenchyme-mesenchyme interactions regulate Msx-1 expression and cellular differentiation in the murine limb bud