Post-transcriptional regulation of the E/Daughterless ortholog HLH-2, negative feedback, and birth order bias during the AC/VU decision in C. elegans

Article Abstract:

The study focuses on the function and regulation of hlh-2, the C-elegans ortholog of Drosophila Daughterless and mammalian E proteins. The role for helix-loop-helix (hlh-2) in promoting transcription of lag-2 is established by obtaining genetic evidence that hlh-2 activity is important for the anchor cell/ventral uterine precursor cell (AC/VU) decision, showing that hlh-2 activity is required for lag-2 expression in the AC, and demonstrating that potential HLH-2 binding sites in the lag-2 promoter are necessary for efficient transcription during the AC/VU decision.

Research and Development in the Physical, Engineering, and Life Sciences, Genetic Engineering

---

A glutamate receptor-interacting protein homolog organizes muscle guidance in Drosophila

Article Abstract:

The establishment of specialized cell-cell junctions plays a determining role in the formation of mature patterned organs in all molecular organisms. The homolog of Glutamate Receptor-Interacting Proteins (DGrip) act as a key component of proper muscle guidance according to an experiment conducted.

Genetic aspects, Glutamate, Homology (Biology), Genetic research

---

Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint

Article Abstract:

The function of the human ortholog of saccharomyces cerevisae Rif1 is reported. The data revealed that human Rif1 contributes to the ATM-mediated protection against DNA damage and point to a remarkable difference in the primary function of the protein in yeast and mammals.

Canada, Food preparations, not elsewhere classified, All Other Miscellaneous Food Manufacturing, Brewers' Yeast, Usage, Brewer's yeast, Saccharomyces cerevisiae, Properties

Similar abstracts:

• Abstracts: Global transcriptional regulation of the locus encoding the skeletal muscle determination genes Mrf4 and Myf5
• Abstracts: Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications
• Abstracts: Case study of the distribution of mucosa- associated Bifidobacterium species, Lactobacillus species and other lactic acid bacteria in the human colon
• Abstracts: Smad transcription factors. Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction
• Abstracts: SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression. LEF1-mediated regulation of Delta-like 1 links Wnt and Notch signaling lin somitogenesis

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.