Reinduction of ErbB2 in astrocytes promotes radial glial progenitor identity in adult cerebral cortex
Article Abstract:
A study on whether re-expression of activated ErbB2 can induce mature astrocytes to revert to a radial glial progenitor phenotype in the adult cerebral cortex is presented. The results indicate a positive response and raise the possibility that reinduced radial glia in the mature brain can be manipulated to generate and guide new neurons.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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Angiomotin regulates endothelial cell migration during embryonic angiogenesis
Article Abstract:
The importance of angiomotin (Amot) during embryonic angiogenesis is studied. Results demonstrate an important role for Amot during tube formation, with defects in endothelial cell (EC) polarization and growth factor-induced migration.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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Comment about this article or add new information about this topic:
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