Repetitive sequences (RPSs) in the chromosomes of Candida albicans are sandwiched between two novel stretches, HOK and RB2, common to each chromosome
Article Abstract:
Two new DNA sequences are discovered in the yeast Candida albicans. These stretches are designated as HOK and RB2. A repetitive sequence (RPS) unique to C. albicans separate the two stretches. HOK and RPSs were found in all C. albicans chromosomes except chromosome 3. The predicted gene product of HOK bears homology with an isocitrate dehydrogenase from Saccharomyces cerevisiae. The RB2 sequence can be found on all chromosomes of C. albicans.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1998
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Analysis of the chromosomal localization of the repetitive sequences (RPSs) in Candida albicans
Article Abstract:
Experimental studies reveal that all chromosomes of Candida albicans, except chromosome 4, have the repetitive sequences (RPSs), which are present within a limited region on each chromosome. Analysis of the digestion of chromosome 6 with SfiI reveals the clustering of RPSs in the middle region of the chromosome 6. Design of a semi-macro physical map of RPSs and their boundary regions on chromosome 6 helps identify the exact location of RPSs.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1995
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The Candida albicans CHS4 gene complements a Sacharomyces cerevisiae skt5/chs4 mutation and is involved in chitin biosynthesis
Article Abstract:
Research was conducted to prove that the Candida albicans CHS4 gene complements a Saccharomyces cerevisiae skt5/chs4 mutation and is involved in chitin biosynthesis. It was demonstrated that ScChs3 activity is enhanced by expression of Chs4p derived from both S. cerevisiae and C. albicans. Results demonstrate that Chs4p is involved in chitin synthase 3 activity by combining with Chs3p to interact synergistically in chitin biosynthesis.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
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