Ribosomal DNA evolution at the population level: nucleotide variation in intergenic spacer arrays of Daphnia pulex
Article Abstract:
DNA sequence variation in ribosomal DNA intergenic spacer (rDNA-IGS) subrepeat arrays from three Daphnia pulex populations from the Midwestern US was investigated. Of the 21 arrays sequenced, 18 contained four subrepeats. Aligning the subrepeats showed that variation was not evenly distributed among subrepeats because the fourth subrepeat was always the short one. There were also short sections of sequence within a particular subrepeat that were more characteristic of another position, suggesting gene conversion. It is suggested that sequence divergence in these subrepeats is intrachromosomal.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1995
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A metabolic basis for dominance and recessivity
Article Abstract:
The theory of genetic dominance has has resulted in numerous hypothetical explanations on its viability. Fisher (1928) proposed an evolutionary pattern for the expression of hereditary genes. Fischer's theory was challenged by Wright (1934) who suggested a sequential series of reactions between alleles and gene expression with metabolism. H. Kacser's research on gene expression based on enzymatic reactions and metabolism has remained as one of the most influencing theories of genetics.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1996
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Epistasis and its contribution to genetic variance components
Article Abstract:
A new parameterization of physiological epistasis confirms that epistasis contributes significantly to genetic variance components, including the additive, dominance and interaction variances. This parameterization of epistasis defines the function of epistasis in the additive genetic variance and thereby helps understand the function of epistasis in evolution.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1995
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