Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression
Article Abstract:
The role of heat-shock factor 2 in cerebral cortex displays mispositioning of neurons of superficial layers. The heat-shock factor 2 affects cellular populations that assist in radial migration and directly regulates the expression of p35, a crucial actor of radial neuronal migration.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2006
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Expansion of adult [beta]-cell mass in response to increased metabolic demand is dependent on HNF-4[alpha]
Article Abstract:
The mutant hepatocyte nuclear factor-4[alpha] (HNF-4[alpha]) gene impairs the proliferation of pancreatic [beta]-cells in maturity-onset diabetes. These findings provide evidence that the gene is responsible for the growth of [beta] cell mass on increased metabolic demand.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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Cell cycle-dependent dynamic localization of a bacterial response regulator with a novel di-guanylate cyclase output domain
Article Abstract:
A study is conducted on dynamic localization of guanylate cyclase. The results propose that local action of novel-type guanylate cyclase might constitute a general regulatory principle in bacterial growth and development.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2004
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- Abstracts: Rates of DNA evolution in Drosophila depend on function and developmental stage of expression. A duplication including the Y allele of Lcp2 and the TRIM retrotransposon at the Lcp locus on the degenerating neo-Y chromosome of Drosophila miranda: molecular structure and mechanisms by which it may have arisen
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