Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface

Article Abstract:

Experimental studies involving genetic perturbation of cellular processes and structure function study of the wingless (Wg) proteins help investigate the Wg signal transduction in Drosophila. Wg proteins exhibits binding with cell surface receptor and transduces signal at the surface of cell. Mutation independently degrades the two specific signaling activities of Wg molecule. Sequence analysis reveals that overall conformation of the Wg molecule regulates the distinct signaling activities. Complex interactions of the Wg ligand with its cell surface receptor molecule exhibit an association with Wg signaling.

Cellular signal transduction

---

Aberrant splicing and transcription termination caused by P element insertion into the intron of the Drosophila gene

Article Abstract:

Examination of P element insertion into the intron of a Drosophila gene suggests a novel mechanism for the P(lacZ, rosy+) element-induced P element mutagenesis. Insertion of the P element into the intron of a gene in the proper orientation stimulates aberrant splicing and transcription termination, producing a mutant phenotype. A mRNA produced from the sequences existing within the element direct aberrant splicing and termination events constitutes 3' sequences from within the P(lac Z, rosy+) element and 5' sequences from the mutated gene.

Introns, Mutagenesis

---

Embryonic transcription and the control of developmental pathways

Article Abstract:

Studies have shown that embryos rely on stored maternal RNA and on zygotically transcribed genetic material to sustain certain genetic activities. Moreover, analysis of several different types of embryos reveals that certain zygotically-derived genes perform unique, controlling roles in embryonic development. Particularly, these genes help control the growth of developmental pathways within the unfertilized eggs.

Genetic transcription, Transcription (Genetics), Developmental genetics, Oogenesis

Similar abstracts:

• Abstracts: Optimizing DNA yield from the buccal swabs in the elderly: attempts to promote buccal cell growth in culture
• Abstracts: Sexual dimorphism in the relationship between number of emerged permanent teeth and percentage of adult stature
• Abstracts: Genetic adaptation to captivity and inbreeding depression in small laboratory populations of Drosophila melanogaster
• Abstracts: Reduced genetic load revealed by slow inbreeding in Drosophila melanogaster. A genetic analysis of intersex, a gene regulating sexual differentiation in Drosophila melanogaster females

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.