Sources for misclassifying genealogical origins in mixed hybrid populations
Article Abstract:
Determination of genealogical origin of hybrid offspring on the basis of genotype analysis alone can be erroneous. The error may occur because the genotype character arrays from advanced generation hybrids and backcrosses overlap arrays from parental crosses and first-generation hybrids. Assignment to a genealogical origin can give classification error rate of 57% and 87% for four and two locus cases, respectively. An error rate of < 5% is achieved by using > 13 loci. Maximum-likelihood method can be used for analysis of hybrid mixtures to obtain unbiased classification estimates.
Publication Name: The Journal of Heredity
Subject: Biological sciences
ISSN: 0022-1503
Year: 1997
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Estimating the frequencies of genetically distinct classes of individuals in hybridized populations
Article Abstract:
An algorithm is developed to examine hybridization and introgression in populations wherein unbiased estimates may be obtained for the frequencies of the two parental species and four first- and second-generation classes of hybrid individuals. A maximum likelihood ratio test is used to detect first-generation introgressants in a population based on the unbiased estimates. Computer simulations have shown that the bootstrap variance estimator is less biased than the delta method for sample sizes less than 200 individuals.
Publication Name: The Journal of Heredity
Subject: Biological sciences
ISSN: 0022-1503
Year: 1993
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Geographic Differentiation in the House Fly Estimated by Microsatellite and Mitochondrial Variation
Article Abstract:
Genetic research on 14 disparate housefly populations from various geographic regions is presented. Findings include no correlation between geographic distance and pairwise genetic distance measures; a comparison between microsatellite and mitochondrial variation is also included.
Publication Name: The Journal of Heredity
Subject: Biological sciences
ISSN: 0022-1503
Year: 2005
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