Structural and functional features of Rhodococcus ruber lipoarabinomannan
Article Abstract:
Results reveal that the immunomodulatory lipoarabinomannan from Rhodococcus ruber is composed of a linear (alpha1---6)-Manp backbone with substitutions at O-2 positions by a t-x-Araf sugar unit. The structure is simpler than that of Mycobacterium tuberculosis lipoarabinomann and the human pathogen R. equi. Furthermore, R. rube lipoarabinomannan cannot induce the production of TNF-x by either human or murine macrophage.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2003
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A role for the PhoBR regulatory system homologue in the Vibrio cholerae phosphate-limitation response and intestinal colonization
Article Abstract:
The Vibrio cholerae PhoBR regulatory system homologue is discussed. Its role in the phosphate-limitation response and in intestinal colonization is of interest. The organism must regulate the expression of genes involved in adaptive responses co-ordinately. Likely members of a two-component regulator family have a role in regulating processes involved in intestinal colonization and pathogenesis for V. cholerae.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
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Molecular analysis of the mannitol operon of Clostridium acetobutylicum encoding a phosphotransferase system and a putative PTS-modulated regulator
Article Abstract:
Molecular analysis of the mannitol operon of Clostridium acetobutylicum encoding a phosphotransferase system has been carried out. It also encodes a putative phosphoenolpyruvate (PEP)-dependent phosphotransferase (PTS)-modulated regulator. C. acetobutylicum DSM 792 accumulates and phosphorylates mannitol through a PTS system. The mannitol operon on C. acetoutylicum DSM 792 has four genes in the order mtlARFD.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2001
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