Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of the actin assembly
Article Abstract:
A study was conducted to determine the structure and physiological function of mammalians' Enabled/vasolidator-stimulated phosphoprotein (VASP) homology 1 (EVH1) domain-peptide complex. Results indicate that the EVH1 domain fold's structure is similar to that of pleckstrin homology domain, which is a membrane localization module. It was also found that EVH1 domains play an active role in the spatial control of actin assembly.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
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Ciboulot regulates actin assembly during Drosophila brain metamorphosis
Article Abstract:
Ciboulot (Cib), a novel actin binding protein, has been found to regulate actin assembly in Drosophila brain metamorphosis. A dynamic actin cytoskeleton is vital for changing cell shape in development. The Cib-actin complex is active in actin filament assembly only at the barbed end. Cib increases actin-based motility in vitro.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2000
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Remodeling of synaptic actin induced by photoconductive stimulation
Article Abstract:
Formation of new active presynaptic terminals of synaptic transmission machinery is demonstrated by video imaging of GFP-actin at individual synapses. Photoconductive stimulation model reveals that a single tetanus moves presynaptic actin toward synaptic junction while postsynaptic actin moving away from it.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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