Suppression of sorbitol dependence in a strain bearing a mutation in the SRB1/PSA1/VIG9 gene encoding GDP-mannose pyrophosphorylase by PDE2 overexpression suggest a role for the Ras/cAMP signal-transduction pathway in the control of yeast cell-wall biogenesis
Article Abstract:
The PSA1/VIG9 gene is the wild-type SRB1 gene in Saccharomyces cerevisiae, not the PDE2 gene. This conclusion supports the role of the Ras/cAMP pathway in cell-wall construction.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Cloning and sequencing of the Candida albicans homologue of SRB1/PSA1/VIG9, the essential gene encoding GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae
Article Abstract:
The gene encoding the GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae is essential. It has been independently isolated as a suppressor of alg1-PSA1 and dpm1 as SRB1. The cloning and molecular characterization of the SRB1.PSA1 homologue from C. albicans has been undertaken. It is shown to be unique in the C. albicans genome and it is suggested that it encodes a highly conserved protein similar to its s. cerevisiae counterpart.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
Down-regulation of the expression of PKC1 and SRB1/PSA1/VIG9, two genes involved in cell wall integrity in Saccharomyces cerevisiae, causes flocculation
Article Abstract:
A study was conducted to analyze the expression of the cell wall integrity determinants PKC1 and SRB1/PSA1/VIG9 of Saccharomyces cerevisiae under the influence of tightly regulated promoter pMET3. The strains were prepared in minimal medium while yeast total RNA was determined and separated on a denaturing agarose gel. Cultures of strains supporting pMET-3 regulated cassettes were grown at 250 rpm and 30 degrees C.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Cloning and sequencing of the gene encoding an aldehyde dehydrogenase that is induced by growing Alteromonas sp. strain KE10 in a low concentration of organic nutrients
- Abstracts: Mixed pollutant degradation by Methylosinus trichosporium OB3b expressing either soluble or particulate methane monooxygenase: Can the tortoise beat the hare?
- Abstracts: Genetic structure and relationships in the snail species complex Littorina arcana Hannaford Ellis, L. compressa Jeffreys and L. saxatilis (Olivi) in the British Isles using SSCPs of cytochrome-b fragments
- Abstracts: Expression of green fluorescent protein in streptococcus gordonii DL1 and its use as a species -specific marker in coadhesion with streptococcus oralis 34 in saliva-conditioned biofilms in vitro
- Abstracts: Spatial and temporal variations in chitinolytic gene expression and bacterial biomass production during chitin degradation