TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism
Article Abstract:
Research has been conducted on tissue inhibitors of metalloproteinases (TIMPs) which suppress the activity of matrix metalloproteinases. The authors report the establishment of the matrix metalloproteinase-independent mechanism for TIMP-2 inhibition of endothelial cell proliferation in vitro.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
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Ubiquitinating a phosphorylated Cdk inhibitor on the blades of the Cdc4 beta-propeller
Article Abstract:
The author discusses substrate binding by ubiquitin ligase which is regulated by phosphorylation. The topics of interest include the crystal structure of Cdc4 subunit bound to high-affinity substrate phosphopeptide.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
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The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by COP9 signalosome in response to DNA damage
Article Abstract:
Research has been conducted on nucleoside excision repair. The authors demonstrate that UV response of the DDB2 and CSA complexes affect nucleoside excision repair mechanism.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
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- Abstracts: Plasmid-mediated mineralization of napthalene, phenanthrene, and anthracene. Evidence for 4-chlorobenzoic acid dehalogenation mediated by plasmid related to pSS50
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