The curious status of the Golgi apparatus
Article Abstract:
The Golgi apparatus is examined to shed some light on the formation of organelle compartments and its impact on the whole endomembrane system of the cell. Evidence indicates that COPII vesicles integrate to create ER-Golgi intermediate compartment or ERGIC clusters, which in turn integrate to develop a new Golgi cisterna. Moreover, each cisterna goes through the stack and finally separates into transport vesicles. All resident Golgi proteins are continuously reused through retrograde vesicles. The Golgi cisternae matures through this vesicular transport.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1998
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Vesicle biogenesis: the coat connection
Article Abstract:
The coats of the vesicles involved in cellular transport are composed of clathrin, coatomer proteins I (COPI) and COPII. The clathrin vesicles transport proteins from the trans-Golgi network to the endosomes. The COPI vesicles control transport from the endoplasmic reticulum to the Golgi complex and COPII vesicles control forward transport. Different proteins are selected into the vesicles depending on the coat protein. COPs may influence the formation of vesicles. Vesicle formation also involves Sec12p, Sar1p and Sed4p.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
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Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network
Article Abstract:
Research has been conducted on the protein kinase D inactive form expressed in HeLa cells. Results indicate that this expression has localized to the trans-Golgi network and produced extensive tubulation.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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