The genetics of epilepsy in the Belgian turvuren and sheepdog

Article Abstract:

Research has been conducted on idiopatic epilepsy in dogs which is characterized by recurrent seizure activity. The authors describe their efforts to establish molecular linkage between the epileptic phenotype and the locus large effect, which have been achieved via genomic DNA screening from affected Belgian turvuren and sheepdogs possessing polymorphic canine microsatellite markers.

Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, Diseases, DNA, Epilepsy, Genetic markers, Phenotype, Phenotypes

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Molecular organization of the canine major histocompatibility complex

Article Abstract:

Research has been conducted on histocompatibility complex composed of tightly linked gene clusters, called dog leukocyte antigen region in dogs. The authors describe the characterization of different loci in dog leukocyte antigen region carried out via canine bacterial artificial chromosome library used for DNA sequencing.

Chromosomes, Molecules, Leukocytes, White blood cells, Antigens, Histocompatibility, Chemical properties

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Canine models of ocular disease: outcross breedings define a dominant disorder present in the English mastiff and bull mastiff dog breeds

Article Abstract:

Research has been conducted on progressive retinal atropies common to both man and dogs. The authors suggest that the genetic origin of this disease is breed specific in dogs, and illustrate that outcross breeding circumvents the problems associated with the study of the disease within a population.

Comparative analysis, Retinal diseases, Population genetics, Genetic research

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