Rapid method to estimate the presence of secondary metabolites in microbial extracts
Article Abstract:
A description is presented of a rapid surrogate method to measure secondary metabolite production, which uses a metabolite productivity index obtained from samples' electrospray mass spectra. This technique is faster than high-performance liquid chromatography analysis, and can be used for identifying improved conditions for cultivation and extraction by enabling researchers to analyze and rank large extract sets.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2001
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Use of direct-infusion electrospray mass spectrometry to guide empirical development of improved conditions for expression of secondary metabolities from actinomycetes
Article Abstract:
An assessment is presented on the ability of rapid, direct-infusion electrospray mass spectrometry (ES-MS) to accurately identify secondary metabolite chemical differences, using 44 actinomycetes cultivated under six separate fermentation conditions. Findings show that the high-throughput ES-MS technique can be used successfully for determining conditions of fermentation that encourage secondary metabolite expression.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2001
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Role of Rhodobacter sp. strain PS9, a purple non-sulfur photosynthetic bacterium isolated from an anaerobic swine waste lagoon, in odor remediation
Article Abstract:
Research shows that the photosynthetic bacterium Rhodobacter sp. strain PS9 can use a variety of organic compounds for its photoorganotrophic growth. Data indicate that the seasonal variations in volatile organic compounds emitted from swine waste lagoons are associated with the bacterium in that during a photosynthetic bloom the odor decreases by 80 to 93%.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2003
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