Virulence characteristics of clinical and environmental isolates of Vibrio vulnificus

Article Abstract:

The virulence of clinical and environmental isolates of Vibrio vulnificus was evaluated using animal model systems. The results showed no significant differences in virulence between the clinical and environmental isolates. The in vivo tests also showed that iron overload, brought about by the bacterium's ability to acquire iron from serum transferrin, is the most significant risk factor in V. vulnificus infections. In vitro experiments showed that the most effective method for differentiating virulence is by a modified agar plate diffusion method testing for the ability to utilize transferrin-bound iron.

Research, Methods, Transferrin, Virulence (Microbiology), Iron, Iron (Metal), Medical microbiology

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Thermal-death times of opaque and translucent morphotypes of Vibrio vulnificus

Article Abstract:

Ninety percent of viable populations of opaque strains of Vibrio vulnificus require more time to be reduced by heating than populations of translucent strains. This indicates that the opaque strains are more heat-resistant than the translucent strains. This finding would lead to better heat-treatment procedures that will completely eliminate the pathogen in foods. V. vulnificus contaminates uncooked seafoods and and is a major cause of cholera outbreaks.

Analysis, Microbial metabolism, Microbial populations

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RpoS-dependent stress response and exoenzyme production in Vibrio vulnificus

Article Abstract:

Research demonstrates that the alternate sigma factor RpoS in Vibrio vulnificus facilitates adaptation to environmental changes and may be even involved in virulence as shown by the RpoS deficient mutant's inability to tolerate stress, decreased exoenzyme synthesis and hydrolytic activities. Furthermore, the motility of the mutant form is highly diminished.

United States, Influence, Stress (Physiology), Enzyme synthesis, Bacterial motility

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