odr-10 encodes a seven transmembrane domain receptor required for response for responses to the odorant diacetyl
Article Abstract:
The selective binding of odorants to various olfactory receptor proteins allows animals to distinguish between closely related enantiomers. The receptors involved in this perceptual process are believed to be G protein-coupled transmembrane domain proteins. In the nematode C. elegans, this is proven to be case, as shown by an examination of the encoding of the odr-10 gene to receptors of the odorant diacetyl. The results provide strong evidence for the view that there exists a specific interaction between odorant ligands and olfactory receptor proteins.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1996
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Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans
Article Abstract:
The nematode C. elegans possesses a highly-specialized sensory system that helps it sort different kinds of sensory information within a single type of sensory neuron. Evidence shows that C. elegans has about 40 receptor genes expressed in its chemosensory neurons. These genes are clustered with similar genes and sensory neurons can express up to four receptors. The neurons respond to a variety of chemicals such a attractants and repellants, which are recognized by the receptor genes.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
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Odorant receptor localization to olfactory cilia is mediated by ODR-4, a novel membrane-associated protein
Article Abstract:
Research was conducted to examine the receptor-specific and cell-type specific localization of seven transmembrane domain receptors to various intracellular compartments or various areas of the plasma membrane. Results revealed the need for the odr-4 and odr-8 genes in localizing receptors to the cilia of olfactory neurons. Other proteins are localized through an odr-4/odr-8-independent pathway.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1998
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