G-protein-coupled receptors as targets for gene transfer vectors using natural small-molecule ligands

Article Abstract:

Researchers from the University of North Carolina used G-protein-coupled receptors as target for vectors in the treatment of cystic fibrosis using small-molecule agonists.

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A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies

Article Abstract:

A framework for comparisons of gene expression data across platforms and laboratories is described. It is demonstrated that after stringent preprocessing, commercial arrays were more consistent than in-house arrays, and by most measures, one dye platforms were more consistent than two-dye platforms.

Forecasts, trends, outlooks, Epilepsy & Muscle Disease R&D, Administration of Public Health Programs, Health Research Programs, Research, Forecasts and trends, Market trend/market analysis, Gene expression, DNA microarrays, Medicine, Experimental

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Analysis of transcription complexes and effects of ligands by microelectrospray ionization mass spectrometry

Article Abstract:

Researchers studied the human vitamin D receptor and retinoid X receptor using rapid buffer exchange gel filtration and microelectrospray ionization mass spectrometry. Charts, graphs, and a photograph are included.

Vitamin, Nutrient & Hematinic Preps, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Brief Article

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