Characterization and identification of vaccine candidate proteins through analysis of the group A Streptococcus surface proteome
Article Abstract:
A study to demonstrate a preteomic approach for identifying bacterial surface-exposed proteins quickly and reliably and their use as vaccine candidates using M1_SF370 group A Streptococcus strain was conducted. When this approach was applied to the sequenced M1_SF370 group A Streptococcus strain, 68 PSORT-predicted surface-associated proteins were identified with number of surface protein varying from strain to strain.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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The next chapter in reverse vaccinology
Article Abstract:
The traditional linear process of testing antigens one at a time has revolutionalized by genome-scale, parallel strategies for discovering candidate antigensan approach known as 'reverse vaccinology'. A study by Rodriguez-Ortega and group push this approach further, by using a combined biochemical, proteomic, and bioinformatics strategy.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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Biomedical informatics for proteomics
Article Abstract:
High quality biological samples and a careful study design is the main requirement for success in proteomics. Implications of biomedical informatics, study design data resources and tools and analysis in research setting are the main focus of the study.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2003
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