Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells
Article Abstract:
A study investigates the involvement of bone morphogenetic protein (BMP) in the early heart formation in the mouse. The findings indicate that the BMP antagonist Noggin is transiently but strongly expressed in heart forming region during gastrulation and acts at the level of induction of mesendoderm to establish conditions conducive to cardiogenesis.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
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Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells
Article Abstract:
The isolation, propagation and directed differentiation of neural crest stem (NCS) cells from human embryonic stem (hES) cells are presented. The observations of the analysis are described which will aid in efforts in tissue engineering, disease modeling and regenerative medicines.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
Article Abstract:
The ability of the cardiomyocytes deduced from human embryonic stem cells in pro-survival factors to improve the function of infarcted rat hearts is discussed.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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