Calorimetric study and modeling of molecular mobility in amorphous organic pharmaceutical compounds using a modified Adam-Gibbs approach
Article Abstract:
The thermal behavior of amorphous organic pharmaceutical compounds across their glass transition temperature is characterized and their molecular mobility is assessed as a function of temperature and time. The Adam-Gibbs method has disclosed the inextricable effect of thermal history on the molecular mobility of the amorphous materials and the ability of the glass to undergo fast changes in its molecular motions.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
A theoretical model for the folding/unfolding thermodynamics of single-domain proteins, based on the quasi-Gaussian entropy theory
Article Abstract:
The framework of the quasi-Gaussian entropy (QGE) theory was used to formulate a general model for the description of the thermodynamic properties of the folding/unfolding of single-domain proteins. This theory provides models for homogeneous fluids, solids, and recently for the thermodynamics of flexible organic molecules in vacuo and solutes.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
Growth dynamics of a liquid crystal at the three- to two-dimensional crossover in a Hele-Shaw cell
Article Abstract:
The radial growth of a cholesteric liquid crystal phase is analyzed in a thick Hele-Shaw cell. It is shown that the growth rate increases at the dimensional crossover, which is approximately constant, independent of the depth of the temperature quench.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Molecular mobility in amorphous maltose and maltitol from phosphorescence of erythrosin B. The effects of film structure and surface hydrogen on the properties of amorphous carbon films
- Abstracts: Influence of artificial periodicity and ionic strength in molecular dynamics simulations of charged biomolecules employing lattice-sum methods
- Abstracts: Raman micro spectrometry as a new approach to the investigation of molecular recognition in solids: chlorofornm-cryptophane complexes
- Abstracts: Atomic layer deposition of HfO2 using alkoxides as precursors. A quantum chemical study of the atomic layer deposition of Al2O3 using AlCl3 and H2O as precursors
- Abstracts: Thermodynamic calculations in the system CH(sub 4)-H(sub 2)O and methane hydrate phase equilibria. The role of water in gas hydrate dissociation