Coarse-grained transmembrane proteins: Hydrophobic matching, aggregation, and their effect on fusion

Article Abstract:

Coarse-grained molecular dynamics model is used in the simulations involving protein-lipid interactions. The results have shown that equilibrium of both water and lipid content is a requirement for spherical vesicles, whereas the simulations have shown that the level of aggregation does not only depend on hydrophobic mismatch, but also on protein shape and one of the proteins promotes fusion by inducing pore formation.

Analysis, Molecular dynamics, Lipid research

---

Proton-coupled electron transfer and tyrosine D of photosystem II

Article Abstract:

The mechanism of proton-coupled electron transfer is studied by performing solvent isotope exchange and measuring kinetic isotope effect on tyrosine D radical ([YD.sup..]) reduction. The modest acceleration in rate at high pL values is attributed to a small, pL-induced change in the distance between [YD.sup..] and proton acceptor ([Q.sub.A.sup.-]).

Electron transport, Tyrosine, Photosystem II

---

Size and shape of detergent micelles determined by small-angle x-ray scattering

Article Abstract:

The aggregation number and shape of micelles formed by nine detergents commonly used in the study of membrane proteins are analyzed. The results have described the determinants of micelle formation and are used as a starting point to correlate detergent properties with detergent-protein interactions.

Optical properties, Micelles, X-ray analysis

Similar abstracts:

• Abstracts: Phase behavior of a "clouding" nonionic polymer in water. Effects of hydrophobic modification and added surfactant on phase compositions
• Abstracts: Use of constrained synthetic amino acids in [beta]-helix proteins for conformational control
• Abstracts: Single particle tracking of complex diffusion in membranes: Simulation and detection of barrier, raft, and interaction phenomena
• Abstracts: X-ray microscopy studies of protein adsorption on a phase segregated polystyrene/polymethylmethacrylate surface. 2: effect of pH on site preference
• Abstracts: Study of molecular behavior in a water nanocluster: Size and temperature effect. part 2 Multiple time-scale behavior of the hydrogen-bond network in water

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.