Retinoic acid induces the degradation of the leukemogenic protein encoded by the promyelocytic leukemia gene fused to the retinoic acid receptor alpha gene

Article Abstract:

Retinoic acid initiates the genetic degradation in acute promyelocytic leukemia. Further aspects of gene mutations in leukemia are discussed.

Physiological aspects, Gene mutations, Gene mutation, Acute leukemia, Promyelocytic, Acute myelocytic leukemia

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The oxidation of 9-cis-retinol: a possible synthesis pathway for 9-cis-retinoic acid

Article Abstract:

This article discusses the genetic aspects of retinoic acid. Topics include pigment epithelium, genetic recombination, and enzyme formation.

California, Genetic aspects, Enzymes, Genetic recombination, Enzyme structure-activity relationships, Retinoids

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A regulatory pathway of thermogenesis in brown fat through retinoic acid

Article Abstract:

Retinoic acid is involved in heat production and in the regulation of energy balance in brown adipose tissue in human bodies. This result occurs because retinoic acid regulates an enzyme, that helps in thermogenesis in brown tissue, through transcriptional regulation. This thermogenesis in brown adipose tissue happens when the enzyme uncouples the respiratory chain from oxidative phosphorylation.

Thermogenesis

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