The effect of fasting and fructose and glucose infusion on gluconeogenesis and triose phosphate flux in rats in vivo

Article Abstract:

Fasting and refeeding change the source and usage of triose phosphate (triose-P) in gluconeogenesis (GNG) to maintain the required concentration of glucose in the body. GNG is controlled by the liver. Fasting in rats inhibits the non-GNG production of glucose in the liver but GNG is unaffected. Fructose infusion increases GNG from triose-P and GNG conversion into glycogen. The conversion of plasma glycerol into triose-P increases during fasting and is suppressed by refeeding. Glucose infusion decreases GNG and the formation of glucose via GNG in the liver.

Physiological aspects, Observations, Glucose, Fasting, Gluconeogenesis, Rats as laboratory animals, Laboratory rats, Glucose synthesis

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The enzymatic cleavage of beta-carotene: still controversial

Article Abstract:

It appears that beta carotene-15, 15'-dioxygenase from intestinal mucosa may bind beta-carotene to produce retinal, though the observed trend may be a result of ransom cleavage. Further research suggests that the conversion of beta-carotene to retinal and retinol may be the result of two different enzymes in the intestinal mucosa. A review of recent research on the process is presented.

Beta carotene, Intestinal mucosa

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The role of oxysterols in cholesterol homeostasis

Article Abstract:

Research presented addresses the role of oxysterols in maintaining cholesterol homeostasis. Studies included suggest excess dietary cholesterol has the effect of increasing oxysterol formation, which in turn binds to a transcription factor that regulates the degradation of cholesterol, activating its removal through the production of bile acids.

Health aspects, Statistical Data Included, Human nutrition, Cholesterol, Essential fatty acids, Essential fatty acids in human nutrition, Sterols, Cholesterol metabolism

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