A 12-year-old boy with progressive nasal obstruction

Article Abstract:

A 12-year-old boy was diagnosed with a benign schwannoma in his nasal cavity. Schwannoma is a tumor originating in the nervous system. He was admitted to a hospital because of a mass in his right nasal cavity that obstructed his breathing. He had begun experiencing breathing difficulty, nosebleeds and headaches when he was 10 years old. A physical exam revealed a mass in his right nasal cavity four months before admission. In the hospital, CT and MRI scans confirmed the presence of the mass. His doctors ruled out a malignant tumor and believed that the mass was a benign tumor called an angiofibroma. However, an angiogram revealed that the tumor did not contain blood vessels. The tumor was surgically removed and microscopic analysis revealed that it was a schwannoma. One year after surgery, the tumor had not recurred.

Nervous system tumors, Head and neck tumors

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A 65-year-old man with a mass that involved the base of the skull

Article Abstract:

A 65-year-old man was diagnosed with multiple myeloma. Patients with multiple myeloma have multiple tumors derived from bone marrow tissue. He had experienced painless double vision 18 months and nine months before admission, but both times regained normal vision without treatment. One month before admission he had experienced pain on the right side of his face, and double vision. A computed tomographic (CT) scan and a magnetic resonance imaging (MRI) scan of his head showed a mass on the right side of his skull. A biopsy of a lesion inside his right nostril revealed a small plasmacytoma, or mass of cancer cells in bone. The patient was treated with radiation therapy and melphalan and prednisone.

Multiple myeloma, Plasmacytoma

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Gastric-outlet obstruction in children

Article Abstract:

Prostaglandin E1 is commonly used to maintain patency of the ductus arteriosus in infants and management of peptic ulcer disease in adults. However, it may also help to cause gastric-outlet syndrome. Infants who developed this problem had received more of the drug cumulatively than infants who did not. Mucus secretion is stimulated by prostaglandin E1. Postmortem examination of an infant who died from gastric-outlet obstruction showed hyperplasia of the gastric pits, especially prominent goblet cells and excessive mucus secretion. The gastric-outlet obstruction was probably caused by both gastric mucosal hypertrophy and mucus accumulation in the stomach.

Editorial, Causes of, Pyloric stenosis, Prostaglandins, Dosage and administration

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