A prognostic score for advanced Hodgkin's disease
Article Abstract:
Some physiological factors may predict which patients with Hodgkin's disease may have a poor prognosis. Researchers analyzed 19 potential prognostic factors in 5,141 patients treated for Hodgkin's disease. Seven factors seemed to be independently associated with progression of disease. They included blood albumin levels, hemoglobin levels, sex, age, disease stage, and white blood cell count. Those with no adverse factors were least likely to experience disease progression and those with five or more were most likely to experience disease progression.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
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A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling
Article Abstract:
A study aims to establish a molecular definition of Burkitt's lymphoma and to search for other clinically relevant subgroups of diffuse large-B-cell lymphoma, using transcriptional and genomic profiling. Results show that in mature aggressive B-cell lymphomas without a gene signature for Burkitt's lymphoma, chromosomal breakpoints at the myc locus were associated with an adverse clinical outcome.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
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Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkin's disease
Article Abstract:
Greater than normal doses of a chemotherapy regimen called BEACOPP may be more effective than a regimen called COPP-ABVD for treating patients with advanced Hodgkin's disease. This was the conclusion of a study of 1,195 patients. BEACOPP contains bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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