A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer
Article Abstract:
A double-blind, randomized trial to test whether, after two to three years of tamoxifen therapy, switching to exemestane was more effective than continuing tamoxifen therapy for the remainder of the five years of treatment. The results showed improved disease-free survival as compared with standard treatment.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
Therapeutic strategies for rheumatoid arthritis
Article Abstract:
The principles needed for the improved understanding of the pathophysiology of rheumatoid arthritis are presented. The clinical application of these principles, which has resulted in a marked improvement in clinical outcomes, is discussed.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
Powerful Genes - Myostatin regulation of human muscle mass
Article Abstract:
A child is described, who at birth, had an unusual muscle definition and size. Myostatin inhibition is an important therapeutic target that may prove beneficial for the treatment of this disorder.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Effects of estrogen therapy on hearing in postmenopausal women
- Abstracts: A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. Letrozole after tamoxifen for breast cancer -- what is the price of success?
- Abstracts: Radical prostatectomy versus watchful waiting in early prostate cancer. Natural history of early, localized prostrate cancer
- Abstracts: Decreased histone deacetylase activity in chronic obstructive pulmonary disease. The nature of small-airway obstruction in Chronic obstructive pulmonary disease (COPD) is a major health problem, which is caused due to excessive exposure to toxic gases and particles. It is concluded that COPD is associated with a thickening of the airway wall, which results in the accumulation of inflammatory exudates in the lumen.
- Abstracts: Two steps forward in the treatment of Colorectal Cancer.. Surveillance strategies after curative treatment of Colorectal Cancer