A two-year-old boy with recurrent infections, cervical lymphadenopathy, and fever

Article Abstract:

A two-year-old boy was diagnosed with chronic granulomatous disease. Chronic granulomatous disease is a genetic disorder characterized by a defect in the killing of engulfed bacteria by white blood cells. This results in increased susceptibility to severe infection. The patient was admitted to the hospital with a fever and enlarged cervical lymph nodes. He had had recurrent infections starting the first weeks of his life. A biopsy of his right large cervical lymph node revealed chronic granulomatous disease. He also had inflammation of the lymph nodes caused by infection with Serratia marcescens. He was treated with antibiotics for the S. marcescens infection. He was also treated with antibiotics and gamma interferon to prevent future infections. Patients with chronic granulomatous disease should avoid wet barns, hay, freshly cut grass and wood shavings to prevent certain types of infections.

Complications and side effects, Bacterial infections, Chronic granulomatous disease, Lymphadenitis

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A 63-year-old man with fever, sweats, and shaking chills

Article Abstract:

A 63-year-old man was diagnosed with babesiosis and Lyme disease. Babesiosis is a tickborne disease caused by protozoa from the genus Babesia. Lyme disease is a tickborne disease caused by the spirochete Borrelia burgdorferi. The patient was admitted to a hospital after developing a fever, chills and fatigue. Six weeks before being admitted to the hospital, he had worked in the garden of his vacation home, which was located in an area with a high incidence of both babesiosis and Lyme disease. He said he had received several insect bites, but noticed no ticks. Microscopic examination of a blood sample revealed that he had babesiosis. A blood test found antibodies against Borrelia burgdorferi.

Lyme disease, Babesiosis

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Nosocomial zoonoses

Article Abstract:

Health care personnel need to use strict infection control procedures while handling animals, including their own pets. A 1998 study reported an outbreak of a fungal infection in a neonatal intensive care unit caused by a yeast organism called Malassezia pachydermatis. An investigation revealed that the organism was probably brought into the unit by health care workers who had dogs who were subsequently found to carry the fungus. There are also cases of hospital infections caused by rats and birds who nest near hospitals as well as by laboratory animals. Regular hand-washing is the best way to prevent such outbreaks.

Editorial, Causes of, Diseases, Zoonoses, Disease transmission, Animals, Nosocomial infections, Cross infection, Animal diseases

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