A 13-year-old girl with gross hematuria four years after a diagnosis of idiopathic pulmonary hemosiderosis
Article Abstract:
A 13-year-old girl with fever, cough and bloody urine was diagnosed with Goodpasture's syndrome. Goodpasture's syndrome is characterized by the circulation of anti-glomerular basement membrane (GBM) antibodies, a rapidly progressive form of kidney disease and pulmonary hemorrhage, which is bleeding of the lungs. Four years prior to admission, the girl was diagnosed with pulmonary hemosiderosis, which is the accumulation of iron in the lungs. On the third day in the hospital, she began coughing up blood and had signs of a lower respiratory tract infection. Further investigation revealed that she had pulmonary hemorrhage and glomerulonephritis, a type of kidney disease. Diseases such as lupus that are associated with immune-complex-related glomerulonephritis were ruled out and so was glomerulonephritis associated with anti-neutrophil cytoplasmic antibodies. She had a kidney biopsy that confirmed the glomerulonephritis, and she tested positive for anti-GBM antibodies.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1993
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Chronic allograft nephropathy
Article Abstract:
About 94% of all people who receive a kidney transplant will develop a kidney disease called chronic allograft nephropathy, according to a study published in 2003. In up to one-third of these cases, the disease is a form of graft rejection. The immunosuppressive drugs these patients must take can also damage the transplanted kidney.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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Case 36-2003: a 68-year-old woman with impaired renal function
Article Abstract:
The case of a 68-year-old woman is presented who developed mild kidney failure after taking ibuprofen. She was treated with dialysis and a corticosteroid drug. She recovered completely.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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