The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice
Article Abstract:
Research has been conducted on the diabetes development in a non-obese mice. Results demonstrate that alpha-galactosylceramide prevents diabetes in the wild-type but not I-like protein-deficient non-obese mice.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune type 1 diabetes
Article Abstract:
Research has been conducted on the type 1 diabetes in non-obese diabetic mice. Results indicate that alpha-galactosylceramide treatment protects female non-obese diabetic mice from type 1 diabetes and prolongs the pancreatic islets survival.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
Article Abstract:
Research shows that the development of airway hyperreactivity requires the activation of pulmonary natural killer T cells, which produce interleukin-4 and interleukin-13. Data indicate that the pulmonary natural killer T cells may aid the lungs leading to type 2 T-helper responses, which mediate the development of airway hyperreactivity and asthma.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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