Adefovir and tenofovir susceptibilities of HIV-1 after 24 to 48 weeks of adefovir dipivoxil therapy: genotypic and phenotypic analyses of study GS-96-408
Article Abstract:
Treatment with the AIDS drug adefovir does not cause mutations in HIV reverse transcriptase but the virus may still become less sensitive to the drug. This was the conclusion of a study of 142 HIV patients.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
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Resistance to protease inhibitors
Article Abstract:
HIV can become resistant to protease inhibitors, which were the third class of drug developed to treat HIV infection. This drug class includes saquinavir, ritonavir, indinavir, nelfinavir, and amprenavir.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
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Comparison of different treatment regimens for the emergence of new resistance under therapy
Article Abstract:
Drug therapy against wild-type HIV may lead to the development of drug resistance and treatment failure. On the other hand, drug therapy against minor strains is less likely to cause resistance.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
User Contributions:
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