Alterations in vitamin D and calcium metabolism with magnesium sulfate treatment of preeclampsia

Article Abstract:

Treatment of preeclampsia, or pregnancy-associated hypertension, with magnesium sulphate may cause a decrease in both maternal and fetal blood levels of calcium. It may also cause an increase in maternal and fetal blood levels of vitamin D and parathyroid hormone. Among 22 pregnant women, 15 were women with preeclampsia who were treated with magnesium sulfate during labor and seven were women without preeclampsia. Before treatment with magnesium sulphate, maternal blood levels of vitamin D and parathyroid hormone were lower in the women with preeclampsia than in the healthy women. Maternal and fetal blood levels of calcium decreased significantly after treatment with magnesium sulfate. Both maternal and fetal blood levels of vitamin D and parathyroid hormone increased significantly after treatment with magnesium sulfate. Magnesium sulfate is used to prevent the development of seizures in pregnant women with preeclampsia.

Complications and side effects, Physiological aspects, Drug therapy, Preeclampsia, Vitamin D, Calcium metabolism, Magnesium sulfate

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Fetoscopic laser ablation of placental vessels in severe previable twin-twin transfusion syndrome

Article Abstract:

Fetoscopic laser ablation of placental blood vessels appears to successfully treat twin-twin transfusion syndrome in some cases. Fetoscopic laser ablation is a surgical procedure in which a laser is used to destroy communicating blood vessels between twins. This syndrome is a rare complication where identical twins share a placenta. Researchers used this technique on 26 pregnant women with confirmed twin-twin transfusion syndrome. Both infants survived in eight cases, one infant survived in nine cases, and neither infant survived in eight cases. The procedure itself may have contributed to or caused deaths in eight cases.

Usage, Evaluation, Surgery, Lasers in surgery, Laser surgery, Fetofetal transfusion, Ablation (Surgery)

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Screening for gestational diabetes mellitus in adolescent pregnancies

Article Abstract:

It may not be cost-effective to screen pregnant teenagers for gestational diabetes. Gestational diabetes is a form of diabetes that first occurs in pregnancy. Researchers used a one-hour oral glucose challenge to screen 509 pregnant teenagers. Twenty-three tested positive and were tested further with a three-hour glucose tolerance test. Six of these women were diagnosed with gestational diabetes, for a rate of about 1%. At a cost per case diagnosed of $2,733, this screening may not be cost-effective in teen populations.

Diagnosis, Testing, Diabetes in pregnancy, Gestational diabetes, Pregnant girls, Pregnant teenagers

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