Hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus

Article Abstract:

Beta blockers may increase the risk of type 2, or adult onset, diabetes. Researchers followed 12,550 adults, 3,804 of whom had hypertension, for six years. After excluding all other risk factors for diabetes, including family history, people who took a beta blocker for their hypertension had a 28% higher risk of developing type 2 diabetes than hypertensive patients who were not on drug therapy. Thiazide diuretics, ACE inhibitors, and calcium channel blockers did not increase the risk of type 2 diabetes.

Complications and side effects, Type 2 diabetes, Adrenergic beta blockers, Adrenergic beta-antagonists, Antihypertensive drugs, Antihypertensive agents

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Association of Sleep-Disordered Breathing, Sleep Apnea, and Hypertension in a Large Community-Based Study

Article Abstract:

People with sleep apnea may have a higher risk of hypertension. People with sleep apnea stop breathing periodically throughout the night. Researchers gave 6,132 patients equipment to measure their breathing and blood oxygen levels at home while they slept. After adjusting for other causes of hypertension, people with the most severe sleep apnea were 37% more likely to have high blood pressure than people with mild sleep apnea. This was true in all age groups and ethnic groups and also in normal-weight and overweight people.

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Is Untreated Sleep Apnea a Contributing Factor for Chronic Hypertension?

Article Abstract:

It may be premature to test all people with hypertension for sleep apnea. Sleep apnea means that people stop breathing momentarily several times throughout the night. It is relatively common, occurring in 10% of women and 25% of men, and often causes no symptoms. A study published in 2000 found that people with hypertension were more likely to have sleep apnea. What remains to be determined is how sleep apnea causes high blood pressure and whether sleep apnea increases mortality from hypertension.

Editorial

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