B cell memory: sapping the T cell
Article Abstract:
Research reveals that the signaling lymphocytic activation molecule-associated protein is involved in the maintenance of antibody levels and memory B cells. The protein binds to the leukocytic receptors and inhibit the receptor interaction with tyrosine phosphatases. Deficiency in this protein leads to immune deficiency.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15
Article Abstract:
Research indicates that the interleukin-15 expanded T cells survive in tumor-bearing severe combined immunodeficiency-Beige mice and mediate eradication of the disseminated intramedullary tumors. Furthermore, transducer T cells from chronic lymphocytic leukemia can lyse autologous tumor cells.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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Dengue immune response: low affinity, high febrility.
Article Abstract:
The immune response of the dengue virus infection is illustrated. Dengue is a mosquito-borne tropical disease caused by four major serotype viruses.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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