Bacterial vaginosis in not important in the etiology of cervical neoplasia: a survey on women with dyskaryotic smears
Article Abstract:
Bacterial vaginosis may not predispose women to develop cervical cancer. Bacterial vaginosis is a condition where bacteria take over the healthy flora of the vagina. Researchers identified bacterial vaginosis in 56 of 280 women (20%) with abnormal cervical Pap smears. Bacterial vaginosis was determined not to cause cervical human papillomavirus (HPV) infection or the development of abnormal cervical cells. Similar risk factors for both bacterial vaginosis and HPV infection, which can lead to cervical cancer, include smoking and the number of sexual partners. Other risk factors for bacterial vaginosis include age when sexual activity first began and the concurrent presence of Chlamydia trachomatis infection. The 20% rate of bacterial vaginosis may be normal among gynecology outpatients.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1995
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Use of a lactoferrin assay in the differential diagnosis of female genital tract infections and implications for the pathophysiology of bacterial vaginosis
Article Abstract:
Testing for lactoferrin in vaginal fluids may prove to be a useful screening technique for certain vaginal infections. White blood cells produce lactoferrin in response to infection. Researchers measured lactoferrin in the vaginal fluids of 57 women, some of whom had trichomoniasis, vaginal yeast infections, or bacterial vaginosis. Using one threshold, the test correctly identified 79% of women with trichomoniasis or bacterial vaginosis and ruled it out in 83% of women. Raising the threshold reduced the percentage of women correctly identified as infected but ruled it out in all women not infected with those diseases.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1996
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Accuracy of cervical/vaginal cytology in the diagnosis of bacterial vaginosis
Article Abstract:
It appears that bacterial vaginosis (BV) can be accurately detected using the Pap smear. Vaginosis is a bacterial infection of the vagina. Clinical signs of BV including vaginal pH, cellular evidence, odor, and milky discharge were compared with Pap smear results from 1,471 women examined between 1990 and 1993. The Pap smear detected nearly all of the 166 identified BV cases with few false-positive and false-negative test results.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1998
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