Molecular biology of the human foamy virus
Article Abstract:
The molecular biology of human foamy virus (HFV) is described. HFV was the first retrovirus to be discovered in 1954. Research on the virus has lagged behind research on other retroviruses, such as HIV. HFV resembles other retroviruses in some respects, but it is also different. One difference is that it does not seem to cause disease in humans. It infects many different cell types and animal species. It also has a longer genome than most other retroviruses. This makes it attractive as a vector for gene transfer.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
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Unexpected replication pathways of foamy viruses
Article Abstract:
Foamy viruses (FV) appear to have important differences from other retroviruses. FVs are widely found in Old and New World apes and monkeys. However, they do not cause any noticeable disease. So far, the viruses have not been found in humans except for a few cases that did not lead to disease. The viruses thus appear to be rather benign. The viruses have replication pathways that differ from other retroviruses. In fact, they appear to be more closely related to pararetroviruses and hepadnaviruses.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
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